Table 4.

Univariate and multivariate Cox proportional hazards analysis for CAPRA-S score risk groups and 16p13.3 gain

McGill cohortUnivariate analysisMultivariate analysis
VariableHR (95% CI)PaHR (95% CI)Pa
CAPRA-S Risk
 Low (0–2) Ref.<0.0001<0.0001
 Intermediate (3–5)3.13 (1.66–5.91)0.00042.91 (1.54–5.51)0.001
 High (≥6)8.94 (4.49–17.79)<0.00017.82 (3.89–15.73)<0.0001
16p13.3 Status (gain vs. no gain)2.30 (1.40–3.78)0.0011.81 (1.09–3.00)0.02
  • Abbreviations: CI, confidence interval; HR, hazard ratio.

  • aWald test.