Table 1.

Caspase-related proteins co-immunoprecipitated with FANCD2 protein

Protein name*Protein IDDescription
PACAPA5A3E0Proapoptotic caspase adaptor protein that interacts and inhibits caspase-3 activity
PKN1NP_002732.3PKN1 is a fatty acid and Rho-activated serine/threonine protein kinase Interacts with TNFα and proteolytically activated by caspase-3
MAP1ANP_002364.5Microtuble-associated protein 1A, in which proteolysis results from the Aβ-mediated activation of caspase-3 and calpain
CalpastatinNP_001139540.1Calpastatin-type II is a highly specific inhibitor of calpain, in which activation is essential for the enzymatic activation of the critical effector caspase-3
NAP1L3NP_004529.2Nucleosome assembly protein 1-like 3 is a substrate for caspase-3
CARD10 (CARMA3)ENSG00000100065Caspase recruitment domain family, member 10
  • *Proteins identified by matrix-assisted laser desorption/ionization–time-of-flight technique in immunopellets of FANCD2-immunoprecipitated cell extracts.