Table 1.

Origin of Telomeres Acquired by Marker der16 Chromosome during B/F/B Cycles

Der16 telomere statusNo. of metaphases (total of 297)% of metaphases
No telomere4917
Telomere acquired
248
83
Mechanism of telomere acquisition
No. of metaphases (total of 248)
% of der16 with telomere
Nonreciprocal translocation6024
Duplication/translocation6024
Reciprocal translocation62
Translocation/donor lost2711
Dicentric83
Small duplication 16q208
No detectable translocation/duplication6728
    One telomere missing*(38)(16)
    All telomeres present*(29)(12)
  • * Status of other chromosomes in the same metaphase spread.