Molecular Cancer Research Targeting the PI3-Kinase Pathway in Cancer
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Future Table of Contents: May 1, 2008; 6 (5)

      Down Subject Reviews
      Down Angiogenesis, Metastasis, and the Cellular Microenvironment
      Down Cancer Genes and Genomics
      Down Cell Cycle, Cell Death, and Senescence
      Down DNA Damage and Cellular Stress Responses
      Down Signaling and Regulation

Subject ReviewsBack

Emily C. Brantley and Etty N. Benveniste
Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas

Harma Feitsma and Edwin Cuppen
Zebrafish as a Cancer Model

Angiogenesis, Metastasis, and the Cellular MicroenvironmentBack

Thuy-Vy Do, Lena A. Kubba, Hongyan Du, Charles D. Sturgis, and Teresa K. Woodruff
Transforming Growth Factor-beta 1, Transforming Growth Factor-beta 2, and Transforming Growth Factor-beta 3 Enhance Ovarian Cancer Metastatic Potential by Inducing a Smad3-Dependent Eptithelial-to-Mesenchymal Transition

Vassiliki Gioni, Theodoros Karampinas, Gerassimos Voutsinas, Andreas E. Roussidis, Savvas Papadopoulos, Nikos K. Karamanos, and Dimitris Kletsas
Imatinib Mesylate Inhibits Proliferation and Exerts an Antifibrotic Effect in Human Breast Stroma Fibroblasts

Xiaohua Shi and Chuanyue Wu
A Suppressive Role of Mitogen Inducible Gene-2 in Mesenchymal Cancer Cell Invasion

Amanda L. Willis, Nhan L. Tran, Julie M. Chatigny, Nichole Charlton, Hong Vu, Sharron A.N. Brown, Michael A. Black, Webndy S. McDonough, Shannon P. Fortin, Joshua R. Niska, Jeffrey A. Winkles, and Heather E. Cunliffe
The Fibroblast Growth Factor-Inducible 14 Receptor Is Highly Expressed in HER2-Positive Breast Tumors and Regulates Breast Cancer Cell Invasive Capacity

Cancer Genes and GenomicsBack

Kristina A. Cole, Edward F. Attiyeh, Yael P. Mosse, Michael J. Laquaglia, Sharon J. Diskin, Garrett M. Brodeur, and John M. Maris
A Functional Screen Identifies miR-34a as a Candidate Neuroblastoma Tumor Suppressor Gene

Francescopaolo Di Cello, Joelle Hillion, Alexandra Hristov, Lisa J. Wood, Mita Mukherjee, Andrew Schuldenfrei, Jeanne Kowalski, Raka Bhattacharya, Rahella Ashfaq, Edward Gabrielson, and Linda M.S. Resar
HMGA2 Participates in Transformation in Human Lung Cancer

Elisa Sala, Luca Mologni, Silvia Truffa, Carlo Gaetano, Gideon E. Bollag, and Carlo Gambacorti-Passerini
BRAF Silencing by Short Hairpin RNA or Chemical Blockade by PLX4032 Leads to Different Responses in Melanoma and Thyroid Carcinoma Cells

Lei Xu, Steven S. Shen, Yujin Hoshida, Aravind Subramanian, Ken Ross, Jean-Philippe Brunet, Stephan N. Wagner, Sridhar Ramaswamy, Jill P. Mesirov, and Richard O. Hynes
Gene Expression Changes in an Animal Melanoma Model Correlate with Aggressiveness of Human Melanoma Metastases

Cell Cycle, Cell Death, and SenescenceBack

Qunfang Li, Lin Tang, Paul Christopher Roberts, Janice M. Kraniak, Aviva Levine Fridman, Olga I. Kulaeva, Omid S. Tehrani, and Michael A. Tainsky
Interferon Regulatory Factors IRF5 and IRF7 Inhibit Growth and Induce Senescence in Immortal Li-Fraumeni Fiborblasts

Alexandros Zafiropoulos, Dragana Nikitovic, Paulos Katonis, aristidis Tsatsakis, Nikas K. Karamanos, and George N. Tzanakakis
Decorin-Induced Growth Inhibition Is Overcome through Protracted Expression and Activation of Epidermal Growth Factor Receptors in Osteosarcoma Cells

DNA Damage and Cellular Stress ResponsesBack

Chad a. Corcoran, Qin He, Suriyan Ponnusamy, Besim Ogretmen, Ying Huang, and M. Saeed Sheikh
Neutral Sphingomyelinase-3 Is a DNA Damage-Regulated and Nongenotoxic Stress-Regulated Gene That Is Deregulated in Human Malignancies

Hong-Lin Devlin, Phillip C. Mack, Rebekah A. Burich, Paul H. Gumerlock, Hsing-Jien Kung, Maria Mudryj, and Ralph W. deVere White
Impairment of the DNA Repair and Growth Arrest Pathways by p53R2 Silencing Enhances DNA Damage-Induced Apoptosis in p53-Dependent Manner in Prostate Cancer Cells

Signaling and RegulationBack

Robert A. Jones, Craig I. Campbell, James J. Petrik, and Roger A. Moorehead
Characterization of a Novel Primary Mammary Tumor Cell Line Reveals that Cyclin D1 Is Regulated by Type I Insulin-Like Growth Factor Receptor

KangAe Lee, Jeremy D. Lynd, Sandra O’Reilly, Matti Kiupel, J. Justin McCormick, and John J. LaPres
The Biphasic Role of the Hypoxia-Inducible Factor Prolyl-4-Hydroxylase, PHD2, in Modulating Tumor-Forming Potential

Hui-Wen Lo, Lisa Stephenson, Xinyu Cao, Mira Milas, Raphael Pollock, and Francis Ali-Osman
Identification and Functional Characterization of the Human Glutathione S-Transferase P1 Gene as a Novel Transcriptional Target of p53 Tumor Suppressor Gene

Jatin K. Nagpal, Sujit Nair, Dimple Chakravarty, Rajib Rajhans, Saikuma Pothana, Darrell W. Brann, Rajeshwar Rao Tekmal, and Ratna K. Vadlamudi
Growth Factor Regulation of Estrogen Receptor Coregulator PELP1 Functions via Protein Kinase A Pathway

Jing Pan, Junhui Zou, Daniel Y.. Wu, Rachael S. Roberson, Leah J. Hennings, Xiaoyun Ma, Marwan Yared, Michael L. Blackburn, Howard A. Chansky, and Liu Yang
TLS-ERG Leukemia Fusion Protein Deregulates Cyclin-Dependent Kinase 1 and Blocks Terminal Differentiation of Myeloid Progenitor Cells

Qun Zhou, Agoston T. Agoston, Peter Atadja, William G. Nelson, and Nancy E. Davidson
Inhibition of Histone Deacetylases Promotes Ubiquitin-Dependent Proteasomal Degradation of DNA Methyltransferase 1 in Human Breast Cancer Cells


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