Aurora B protein kinase is a member of chromosomal passenger complex and a survivin-binding partner regulating mitotic events including chromosome segregation and cytokinesis. This kinase displays a characteristic localization pattern in mitotic cells as it is present at metaphase chromosomes, central spindle midzone, and midbody. Bcr-Abl-expressing mouse progenitor cells were stained with anti-Aurora B antibody (red) followed by DNA staining with DAPI (blue). Mitotic cell in metaphase is presented. Original magnification, ×200. For details, see the article by Wolanin et al. on page 457.

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