Subject Review:

Ubiquitin Hubs in Oncogenic Networks

Nicola Crosetto, Marzena Bienko, and Ivan Dikic
Mol Cancer Res 2006 4: 899-904 doi: 10.1158/1541-7786.MCR-06-0328 [Abstract] [Full Text] [PDF]  

Angiogenesis, Metastasis, and the Cellular Microenvironment:

Use of an Aggressive MCF-7 Cell Line Variant, TMX2-28, to Study Cell Invasion in Breast Cancer

Joseph M. Gozgit, Brian T. Pentecost, Sharon A. Marconi, Christopher N. Otis, Chuanyue Wu, and Kathleen F. Arcaro
Mol Cancer Res 2006 4: 905-913 doi: 10.1158/1541-7786.MCR-06-0147 [Abstract] [Full Text] [PDF]  

Expression of the Receptor Tyrosine Kinase Tie2 in Neoplastic Glial Cells Is Associated with Integrin ß1-Dependent Adhesion to the Extracellular Matrix

Ok-Hee Lee, Jing Xu, Juan Fueyo, Gregory N. Fuller, Kenneth D. Aldape, Marta M. Alonso, Yuji Piao, Ta-Jen Liu, Frederick F. Lang, B. Nebiyou Bekele, and Candelaria Gomez-Manzano
Mol Cancer Res 2006 4: 915-926 doi: 10.1158/1541-7786.MCR-06-0184 [Abstract] [Full Text] [PDF]  

Cancer Genes and Genomics:

Amplification of KIT, PDGFRA, VEGFR2, and EGFR in Gliomas

Marjut Puputti, Olli Tynninen, Harri Sihto, Tea Blom, Hanna Mäenpää, Jorma Isola, Anders Paetau, Heikki Joensuu, and Nina N. Nupponen
Mol Cancer Res 2006 4: 927-934 doi: 10.1158/1541-7786.MCR-06-0085 [Abstract] [Full Text] [PDF]  

Cell Cycle, Cell Death, and Senescence:

Fbw7 Isoform Interaction Contributes to Cyclin E Proteolysis

Wei Zhang and Deanna M. Koepp
Mol Cancer Res 2006 4: 935-943 doi: 10.1158/1541-7786.MCR-06-0253 [Abstract] [Full Text] [PDF] Supplementary Data  

DNA Damage and Cellular Stress Responses:

Nuclear Factor-B p65 Inhibits Mitogen-Activated Protein Kinase Signaling Pathway in Radioresistant Breast Cancer Cells

Kazi M. Ahmed, Shaozhong Dong, Ming Fan, and Jian Jian Li
Mol Cancer Res 2006 4: 945-955 doi: 10.1158/1541-7786.MCR-06-0291 [Abstract] [Full Text] [PDF]  

Model Organisms:

Bub1 Up-Regulation and Hyperphosphorylation Promote Malignant Transformation in SV40 Tag–Induced Transgenic Mouse Models

Conghui Guo, Guojun Wu, Joseph L. Chin, Glenn Bauman, Madeleine Moussa, Feng Wang, Norman M. Greenberg, Stephen S. Taylor, and Jim W. Xuan
Mol Cancer Res 2006 4: 957-969 doi: 10.1158/1541-7786.MCR-06-0168 [Abstract] [Full Text] [PDF]  

Effect of an Epidermal Growth Factor Receptor Inhibitor in Mouse Models of Lung Cancer

Ying Yan, Yan Lu, Min Wang, Haris Vikis, Ruisheng Yao, Yian Wang, Ronald A. Lubet, and Ming You
Mol Cancer Res 2006 4: 971-981 doi: 10.1158/1541-7786.MCR-06-0086 [Abstract] [Full Text] [PDF] Supplementary Data  

Signaling and Regulation:

Peptide Aptamers with Binding Specificity for the Intracellular Domain of the ErbB2 Receptor Interfere with AKT Signaling and Sensitize Breast Cancer Cells to Taxol

Christian Kunz, Corina Borghouts, Claudia Buerger, and Bernd Groner
Mol Cancer Res 2006 4: 983-998 doi: 10.1158/1541-7786.MCR-06-0046 [Abstract] [Full Text] [PDF]  

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