In vivo vascularization of matrigel containing heparin, nucleosomes or fibroblast growth factor-2, FGF-2. Eight-week-old athymic nu/nu mice were s.c. injected in the ventral midline region with 0.4 ml matrigel containing 25 U/ml heparin, 50 µg/ml nucleosomes or 100 ng/ml FGF-2. Ten days later, matrigel plugs were excised from the mice and photographed. The level of blood vessel formation is noted by the degree of red color and the presence of vascular structures within the matrigel plug. For details, see the article by Tanner et al. on page 281.

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