Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Jonathan B. Bell; Frank Eckerdt; Harshil D. Dhruv; Darren Finlay; Sen Peng; Seungchan Kim; Barbara Kroczynska; Elspeth M. Beauchamp; Kristen Alley; Jessica Clymer; Stewart Goldman; Shi-Yuan Cheng; C. David James; Ichiro Nakano; Craig Horbinski; Andrew P. Mazar; Kristiina Vuori; Priya Kumthekar; Jeffrey Raizer; Michael E. Berens; Leonidas C. Platanias

doi:10.1158/1541-7786.MCR-17-0397

Cell Death and Survival

Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Jonathan B. Bell, Frank Eckerdt, Harshil D. Dhruv, Darren Finlay, Sen Peng, Seungchan Kim, Barbara Kroczynska, Elspeth M. Beauchamp, Kristen Alley, Jessica Clymer, Stewart Goldman, Shi-Yuan Cheng, C. David James, Ichiro Nakano, Craig Horbinski, Andrew P. Mazar, Kristiina Vuori, Priya Kumthekar, Jeffrey Raizer, Michael E. Berens and Leonidas C. Platanias

Jonathan B. Bell

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Frank Eckerdt

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Harshil D. Dhruv

Cancer and Cell Biology Division, The Translational Genomics Research Institute, Phoenix, Arizona.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Darren Finlay

Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Sen Peng

Cancer and Cell Biology Division, The Translational Genomics Research Institute, Phoenix, Arizona.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Seungchan Kim

Integrated Cancer Genomics Division, The Translational Genomics Research Institute, Phoenix, Arizona.Department of Electrical and Computer Engineering, Roy G. Perry College of Engineering, Prairie View A&M University, Prairie View, Texas.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Barbara Kroczynska

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Elspeth M. Beauchamp

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Medicine, Jesse Brown VA Medical Center, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kristen Alley

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jessica Clymer

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Division of Hematology/Oncology/Stem Cell Transplantation, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Stewart Goldman

Division of Hematology/Oncology/Stem Cell Transplantation, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Shi-Yuan Cheng

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

C. David James

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Ichiro Nakano

Department of Neurosurgery and Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Craig Horbinski

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Andrew P. Mazar

Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Developmental Therapeutics Core, Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Kristiina Vuori

Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Priya Kumthekar

Division of Neuro-Oncology, Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Jeffrey Raizer

Division of Neuro-Oncology, Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Michael E. Berens

Cancer and Cell Biology Division, The Translational Genomics Research Institute, Phoenix, Arizona.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site

Leonidas C. Platanias

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
For correspondence: l-platanias@northwestern.edu

DOI: 10.1158/1541-7786.MCR-17-0397 Published January 2018

Article
Figures & Data
Info & Metrics
PDF

Log in using your username and password

Username *

Password *

Forgot your user name or password?

Purchase Short Term Access

Pay Per Article - You may access this article (from the computer you are currently using) for 1 day for US$35.00

Regain Access - You can regain access to a recent Pay per Article purchase if your access period has not yet expired.

PreviousNext

January 2018
Volume 16, Issue 1

Table of Contents
Table of Contents (PDF)
About the Cover
Index by Author
Editorial Board (PDF)

Search for this keyword

View this article with LENS

Open full page PDF

Article Alerts

User Name *

Password *

Email *

Email Article

Thank you for sharing this Molecular Cancer Research article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Message Subject (Your Name) has forwarded a page to you from Molecular Cancer Research

Message Body (Your Name) thought you would be interested in this article in Molecular Cancer Research.

Your Personal Message

Citation Tools

Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Mol Cancer Res January 1 2018 (16) (1) 32-46; DOI: 10.1158/1541-7786.MCR-17-0397

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Mol Cancer Res January 1 2018 (16) (1) 32-46; DOI: 10.1158/1541-7786.MCR-17-0397

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Jump to section

Article
Figures & Data
Info & Metrics
PDF

Main menu

User menu

Search

Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Purchase Short Term Access

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Articles

Information for

About MCR