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Molecular Cancer Research

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Cell Death and Survival

Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Jonathan B. Bell, Frank Eckerdt, Harshil D. Dhruv, Darren Finlay, Sen Peng, Seungchan Kim, Barbara Kroczynska, Elspeth M. Beauchamp, Kristen Alley, Jessica Clymer, Stewart Goldman, Shi-Yuan Cheng, C. David James, Ichiro Nakano, Craig Horbinski, Andrew P. Mazar, Kristiina Vuori, Priya Kumthekar, Jeffrey Raizer, Michael E. Berens and Leonidas C. Platanias
Jonathan B. Bell
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Frank Eckerdt
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Harshil D. Dhruv
Cancer and Cell Biology Division, The Translational Genomics Research Institute, Phoenix, Arizona.
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Darren Finlay
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
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Sen Peng
Cancer and Cell Biology Division, The Translational Genomics Research Institute, Phoenix, Arizona.
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Seungchan Kim
Integrated Cancer Genomics Division, The Translational Genomics Research Institute, Phoenix, Arizona.Department of Electrical and Computer Engineering, Roy G. Perry College of Engineering, Prairie View A&M University, Prairie View, Texas.
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Barbara Kroczynska
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Elspeth M. Beauchamp
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Medicine, Jesse Brown VA Medical Center, Chicago, Illinois.
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Kristen Alley
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Jessica Clymer
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Division of Hematology/Oncology/Stem Cell Transplantation, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
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Stewart Goldman
Division of Hematology/Oncology/Stem Cell Transplantation, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
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Shi-Yuan Cheng
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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C. David James
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Ichiro Nakano
Department of Neurosurgery and Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama.
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Craig Horbinski
Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Andrew P. Mazar
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Developmental Therapeutics Core, Center for Developmental Therapeutics, Northwestern University, Evanston, Illinois.
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Kristiina Vuori
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.
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Priya Kumthekar
Division of Neuro-Oncology, Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Jeffrey Raizer
Division of Neuro-Oncology, Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
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Michael E. Berens
Cancer and Cell Biology Division, The Translational Genomics Research Institute, Phoenix, Arizona.
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Leonidas C. Platanias
Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.Department of Medicine, Jesse Brown VA Medical Center, Chicago, Illinois.
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  • For correspondence: l-platanias@northwestern.edu
DOI: 10.1158/1541-7786.MCR-17-0397 Published January 2018
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Molecular Cancer Research: 16 (1)
January 2018
Volume 16, Issue 1
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Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation
Jonathan B. Bell, Frank Eckerdt, Harshil D. Dhruv, Darren Finlay, Sen Peng, Seungchan Kim, Barbara Kroczynska, Elspeth M. Beauchamp, Kristen Alley, Jessica Clymer, Stewart Goldman, Shi-Yuan Cheng, C. David James, Ichiro Nakano, Craig Horbinski, Andrew P. Mazar, Kristiina Vuori, Priya Kumthekar, Jeffrey Raizer, Michael E. Berens and Leonidas C. Platanias
Mol Cancer Res January 1 2018 (16) (1) 32-46; DOI: 10.1158/1541-7786.MCR-17-0397

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Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation
Jonathan B. Bell, Frank Eckerdt, Harshil D. Dhruv, Darren Finlay, Sen Peng, Seungchan Kim, Barbara Kroczynska, Elspeth M. Beauchamp, Kristen Alley, Jessica Clymer, Stewart Goldman, Shi-Yuan Cheng, C. David James, Ichiro Nakano, Craig Horbinski, Andrew P. Mazar, Kristiina Vuori, Priya Kumthekar, Jeffrey Raizer, Michael E. Berens and Leonidas C. Platanias
Mol Cancer Res January 1 2018 (16) (1) 32-46; DOI: 10.1158/1541-7786.MCR-17-0397
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