Molecular Cancer Research: 15 (3)

Highlights

Highlights

Highlights of This Issue

Mol Cancer Res March 1 2017 15 (3) 235-235;

Cell Cycle and Senescence

Cell Cycle and Senescence

Stromal Senescence By Prolonged CDK4/6 Inhibition Potentiates Tumor Growth

Xiangnan Guan, Kyle M. LaPak, Rebecca C. Hennessey, Christina Y. Yu, Reena Shakya, Jianying Zhang and Christin E. Burd

Mol Cancer Res March 1 2017 15 (3) 237-249; DOI:10.1158/1541-7786.MCR-16-0319

Cell Death and Survival

Cell Death and Survival

Autophagy Inhibition Enhances Sunitinib Efficacy in Clear Cell Ovarian Carcinoma

Lindsay DeVorkin, Matthew Hattersley, Paul Kim, Jenna Ries, Jaeline Spowart, Michael S. Anglesio, Samuel M. Levi, David G. Huntsman, Ravi K. Amaravadi, Jeffrey D. Winkler, Anna V. Tinker and Julian J. Lum

Mol Cancer Res March 1 2017 15 (3) 250-258; DOI:10.1158/1541-7786.MCR-16-0132
Cell Death and Survival | AuthorChoice

Key Survival Factor, Mcl-1, Correlates with Sensitivity to Combined Bcl-2/Bcl-xL Blockade

Michelle M. Williams, Linus Lee, Donna J. Hicks, Meghan M. Joly, David Elion, Bushra Rahman, Courtney McKernan, Violeta Sanchez, Justin M. Balko, Thomas Stricker, Monica Valeria Estrada and Rebecca S. Cook

Mol Cancer Res March 1 2017 15 (3) 259-268; DOI:10.1158/1541-7786.MCR-16-0280-T

DNA Damage and Repair

DNA Damage and Repair

DNA Polymerase Beta Germline Variant Confers Cellular Response to Cisplatin Therapy

Antonia A. Nemec, Laura Abriola, Jane S. Merkel, Elisa de Stanchina, Michelle DeVeaux, Daniel Zelterman, Peter M. Glazer and Joann B. Sweasy

Mol Cancer Res March 1 2017 15 (3) 269-280; DOI:10.1158/1541-7786.MCR-16-0227-T

Genomics

Genomics

Pathology-Driven Comprehensive Proteomic Profiling of the Prostate Cancer Tumor Microenvironment

Lisa Staunton, Claire Tonry, Rosina Lis, Virginia Espina, Lance Liotta, Rosanna Inzitari, Michaela Bowden, Aurelie Fabre, John O'Leary, Stephen P. Finn, Massimo Loda and Stephen R. Pennington

Mol Cancer Res March 1 2017 15 (3) 281-293; DOI:10.1158/1541-7786.MCR-16-0358

Oncogenes and Tumor Suppressors

Oncogenes and Tumor Suppressors | AuthorChoice

LIN28B Activation by PRL-3 Promotes Leukemogenesis and a Stem Cell–like Transcriptional Program in AML

Jianbiao Zhou, Zit-Liang Chan, Chonglei Bi, Xiao Lu, Phyllis S.Y. Chong, Jing-Yuan Chooi, Lip-Lee Cheong, Shaw-Cheng Liu, Ying Qing Ching, Yafeng Zhou, Motomi Osato, Tuan Zea Tan, Chin Hin Ng, Siok-Bian Ng, Shi Wang, Qi Zeng and Wee-Joo Chng

Mol Cancer Res March 1 2017 15 (3) 294-303; DOI:10.1158/1541-7786.MCR-16-0275-T
Oncogenes and Tumor Suppressors

Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC

Leandro N. Güttlein, Lorena G. Benedetti, Cristóbal Fresno, Raúl G. Spallanzani, Sabrina F. Mansilla, Cecilia Rotondaro, Ximena L. Raffo Iraolagoitia, Edgardo Salvatierra, Alicia I. Bravo, Elmer A. Fernández, Vanesa Gottifredi, Norberto W. Zwirner, Andrea S. Llera and Osvaldo L. Podhajcer

Mol Cancer Res March 1 2017 15 (3) 304-316; DOI:10.1158/1541-7786.MCR-16-0243-T
Oncogenes and Tumor Suppressors

Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations

Tyler M. Foley, Susan N. Payne, Cheri A. Pasch, Alex E. Yueh, Dana R. Van De Hey, Demetra P. Korkos, Linda Clipson, Molly E. Maher, Kristina A. Matkowskyj, Michael A. Newton and Dustin A. Deming

Mol Cancer Res March 1 2017 15 (3) 317-327; DOI:10.1158/1541-7786.MCR-16-0256-T
Oncogenes and Tumor Suppressors

Functional Activation of Mutant p53 by Platinum Analogues in Cisplatin-Resistant Cells Is Dependent on Phosphorylation

Xiaolei Xie, Guangan He and Zahid H. Siddik

Mol Cancer Res March 1 2017 15 (3) 328-339; DOI:10.1158/1541-7786.MCR-16-0257-T

Signal Transduction

Signal Transduction

Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors

Monica E. Wielgos, Rajani Rajbhandari, Tiffiny S. Cooper, Shi Wei, Susan Nozell and Eddy S. Yang

Mol Cancer Res March 1 2017 15 (3) 340-347; DOI:10.1158/1541-7786.MCR-16-0287-T
Signal Transduction

Nuclear Import of JAK1 Is Mediated by a Classical NLS and Is Required for Survival of Diffuse Large B-cell Lymphoma

Fen Zhu, Byounghoon Hwang, Shigeki Miyamoto and Lixin Rui

Mol Cancer Res March 1 2017 15 (3) 348-357; DOI:10.1158/1541-7786.MCR-16-0344

Retraction

Retraction | Free Article

Retraction: Nek6 Mediates Human Cancer Cell Transformation and Is a Potential Cancer Therapeutic Target

Mol Cancer Res March 1 2017 15 (3) 358-358; DOI:10.1158/1541-7786.MCR-16-0440

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Highlights

Cell Cycle and Senescence

Cell Death and Survival

DNA Damage and Repair

Genomics

Oncogenes and Tumor Suppressors

Signal Transduction

Retraction

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