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Table of Contents

Highlights

Highlights

Highlights of This Issue

Mol Cancer Res August 1 2016 14 (8) 673-673;

Perspective

Perspective | AuthorChoice

Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance

The Cancer Target Discovery and Development Network

Mol Cancer Res August 1 2016 14 (8) 675-682; DOI:10.1158/1541-7786.MCR-16-0090

Cell Cycle and Senescence

Cell Cycle and Senescence | AuthorChoice

AMPK Causes Cell Cycle Arrest in LKB1-Deficient Cells via Activation of CAMKK2

Sarah Fogarty, Fiona A. Ross, Diana Vara Ciruelos, Alexander Gray, Graeme J. Gowans and D. Grahame Hardie

Mol Cancer Res August 1 2016 14 (8) 683-695; DOI:10.1158/1541-7786.MCR-15-0479

Cell Death and Survival

Cell Death and Survival | AuthorChoice

Role for the Aryl Hydrocarbon Receptor and Diverse Ligands in Oral Squamous Cell Carcinoma Migration and Tumorigenesis

Elizabeth A. Stanford, Alejandra Ramirez-Cardenas, Zhongyan Wang, Olga Novikov, Khalid Alamoud, Petros Koutrakis, Joseph P. Mizgerd, Caroline A. Genco, Maria Kukuruzinska, Stefano Monti, Manish V. Bais and David H. Sherr

Mol Cancer Res August 1 2016 14 (8) 696-706; DOI:10.1158/1541-7786.MCR-16-0069

Chromatin, Epigenetics, and RNA Regulation

Chromatin, Epigenetics, and RNA Regulation

GR and ER Coactivation Alters the Expression of Differentiation Genes and Associates with Improved ER⁺ Breast Cancer Outcome

Diana C. West, Deng Pan, Eva Y. Tonsing-Carter, Kyle M. Hernandez, Charles F. Pierce, Sarah C. Styke, Kathleen R. Bowie, Tzintzuni I. Garcia, Masha Kocherginsky and Suzanne D. Conzen

Mol Cancer Res August 1 2016 14 (8) 707-719; DOI:10.1158/1541-7786.MCR-15-0433

Genomics

Genomics

An Integrative Approach Uncovers Biomarkers that Associate with Clinically Relevant Disease Outcomes in Vulvar Carcinoma

Andre M. Lavorato-Rocha, Erica M. Akagi, Beatriz de Melo Maia, Iara S. Rodrigues, Mayara Caroline Silva Botelho, Fabio A. Marchi, Gabriel Fernandes, Glauco Baiocchi, Fernando A. Soares, Silvia Regina Rogatto, Yukie Sato-Kuwabara and Rafael M. Rocha

Mol Cancer Res August 1 2016 14 (8) 720-729; DOI:10.1158/1541-7786.MCR-15-0366

Oncogenes and Tumor Suppressors

Oncogenes and Tumor Suppressors

CITED2 Modulates Breast Cancer Metastatic Ability through Effects on IKKα

Swaathi Jayaraman, Michele Doucet, Wen Min Lau and Scott L. Kominsky

Mol Cancer Res August 1 2016 14 (8) 730-739; DOI:10.1158/1541-7786.MCR-16-0081
Oncogenes and Tumor Suppressors

A Novel EGFR Extracellular Domain Mutant, EGFRΔ768, Possesses Distinct Biological and Biochemical Properties in Neuroblastoma

James Keller, Anjaruwee S. Nimnual, Mathew S. Varghese, Kristen A. VanHeyst, Michael J. Hayman and Edward L. Chan

Mol Cancer Res August 1 2016 14 (8) 740-752; DOI:10.1158/1541-7786.MCR-15-0477

Signal Transduction

Signal Transduction

JNK1 Inhibition Attenuates Hypoxia-Induced Autophagy and Sensitizes to Chemotherapy

Irina A. Vasilevskaya, Muthu Selvakumaran, David Roberts and Peter J. O'Dwyer

Mol Cancer Res August 1 2016 14 (8) 753-763; DOI:10.1158/1541-7786.MCR-16-0035